Cilastatin Monosodium Salt

《英文msh詞典》Cilastatin Monosodium Salt
[入口詞] Cilastatin Monosodium Salt
[主題詞] Cilastatin
[藥動學] Protease Inhibitors
[英文釋義] A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic,IMIPENEM,is hydrolyzed by dehydropeptidase-I,which resides in the brush border of the renal tubule,cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukeotriene E4.

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